Novel microRNA Biomarker Signature in Extracellular Vesicles for Atherosclerosis Detection
Posted on October 12, 2021
In cooperation with Prof. Dr. Gustav Schelling's group at the hospital of the Ludwig-Maximilians-University (LMU) Munich, Prof. Dr. Michael Pfaffl's group at the Technical University of Munich (TUM) and the company TIB MOLBIOL, we detected a new microRNA biomarker signature for risk assessment of arteriosclerosis and its sequelae. The first results are now published in Frontiers in Cell and Developmental Biology. This project was funded by ZIM, Germany's largest innovation programme for small and medium-sized enterprises. 'ZIM' stands for 'Zentrales Innovationsprogramm Mittelstand', which means 'Central Innovation Programme for small and medium-sized enterprises (SMEs)'. It is a funding programme of the Federal Ministry for Economic Affairs and Energy (BMWi) that aims to foster the innovative capacity of SMEs.
Reference:
Hildebrandt A, Kirchner B, Meidert A, Brandes F, Lindemann A, Doose G, Doege A, Weidenhagen R, Reithmair M, Schelling G, Pfaffl M: 'Detection of Atherosclerosis by Small RNA-Sequencing Analysis of Extracellular Vesicle Enriched Serum Samples', Front. Cell Dev. Biol. 10.3389/fcell.2021.729061 (2021)